Ibicuruzwa

Tulathromycine, ni antibacterial agent yagutse ifite ibikorwa bya antibacterial kurwanya bagiteri zimwe na zimwe na Gram-mbi.Byumva cyane cyane indwara ziterwa n'ubuhumekero mu nka no mu ngurube, nka Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, ibitotsi bya histophilus (ibitotsi bya Haemophilus), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchise.

Ibiranga pharmacokinetic biranga Tulathromycine ni uko nyuma yubuyobozi bumwe, bwinjizwa vuba aha batewe inshinge, ubwinshi bwamaraso bukomeza kubikwa igihe kirekire, kurandura buhoro, ubwinshi bwikwirakwizwa ni bunini, bioavailable iri hejuru, kandi kwibumbira mubice bya periferiya birenze ibyo muri plasma.Ikwirakwizwa ryinshi ryimitsi hamwe ningirabuzimafatizo nziza ni ibintu byingenzi biranga metabolism ya Tulathromycin.Kwiyongera mu ngirabuzimafatizo na byo ni ikintu cy'ingenzi kiranga Tulathromycine.

Tulathromycin ibuza intungamubiri za poroteyine za bagiteri guhagarika inzira ya transfert ya peptide.Kubera inenge zimwe na zimwe za erythromycine, abantu bakeneye undi muti aho kuba erythromycine byihutirwa.Tulathromycin ni ubwoko bushya bwa macrolide igice cya sintetike ya antibiotike yinyamaswa.Ifite ibyiza byinshi, nka dosiye nkeya, ubuyobozi bwigihe kimwe, ibisigara bike, inyamanswa yihariye nibindi.Ntabwo ifite ibyiza byimiti ya macrolide gusa, ahubwo ifite ultra ndende yubuzima burenze iyindi antibiyotike ya macrolide.Ishingiye ku nyungu zo gukomeza kuvura neza mu mubiri igihe kirekire, irashobora kugera kuri bacteriostasis nziza na sterilisation.

Nyuma yo gukoreshwa kwa muganga, tulathromycine igira ingaruka zigaragara zo kuvura indwara zubuhumekero zinka ningurube.Urakoze kubikorwa byiza bya antibacterial ya Tulathromycine nka dosiye ntoya ukoresheje, igihe kirekire cyubuzima hamwe nubuyobozi bwigihe kimwe, irashobora gukoreshwa cyane.

Tulathromycine irakomeye kuruta macrolide ikoreshwa cyane ku isoko muri iki gihe, nka tylosine, tilmicosine na florfenicol.Nibishobora gukoreshwa cyane.

Witondere kwitabwaho ko Tulathromycine ifite umutekano muke, idafite kanseri, teratogenicity na genotoxicity.Ntabwo bizatera ihinduka rya gene, ariko birashobora kubyara umutima.Ukeneye gukurikiza inama zamatungo.