Imiyoboro ya Laboratoire

Ibicuruzwa

Tofacitinib citrate 540737-29-9 Rheumatoid arthritis Anticancer

Ibisobanuro bigufi:

Synonyme:CP-690550 (Citrate ya Tofacitinib); (3R, 4R) -1- (Cyanoacetyl) -4-methyl-N-methyl-N-1H-pyrrolo -hidroxy-1,2,3-propanetricarboxylate

CAS No.:540737-29-9

Ubwiza:mu nzu

Inzira ya molekulari:C16H20N6O.C6H8O7

Uburemere bwa formula:504.49


Ibicuruzwa birambuye

Ibicuruzwa

Kwishura:T / T, L / C.
Inkomoko y'ibicuruzwa:Ubushinwa
Icyambu cyo kohereza:Beijing / Shanghai / Hangzhou
Ubushobozi bwo gukora:100kg / ukwezi
Tegeka (MOQ):25kg
Igihe cyo kuyobora:Iminsi y'akazi
Imiterere y'ububiko:Ubitswe ahantu hakonje, humye, ubushyuhe bwicyumba.
Ibikoresho bipakira:ingoma
Ingano yububiko:25kg/ingoma
Amakuru yumutekano:Ntabwo ari ibintu biteje akaga

Tofacitinib citrate

Intangiriro

Tofacitinib, ni imiti ikoreshwa mu kuvura rubagimpande ya rubagimpande, arthrite ya psoriatic, na colitis ulcerative.

Citrate ya Tofacitinib ikoreshwa mu kuvura abantu bakuru bafite rubagimpande ya rubagimpande ya rubagimpande zidafite ibisubizo bidahagije, cyangwa batihanganira methotrexate.

Citrate ya Tofacitinib yerekanwa mu kuvura indwara ya rubagimpande (RA) ikabije kandi ikabije ku bantu bakuze bitabiriye bihagije, cyangwa batihanganira imiti imwe cyangwa myinshi ihindura indwara imiti igabanya ubukana.

Ibisobanuro (mu nzu)

Ingingo

Ibisobanuro

Kugaragara

Ifu yera cyangwa yera-ifu ya kristaline

Kumenyekanisha

IR, HPLC

Amazi

.5 1.5%

Ibintu bifitanye isano

TOFA 06 ≤0.15%

Tofacitinib trans isomer ≤0.15%

Tofacitinib idafite umwuma ≤0.15%

Buri mwanda utazwi ≤0,10%

Impanuka zose: ≤1.0%

Ibisigisigi bisigaye

Ethanol ≤5000ppm

Benzene ≤2ppm

Toluene ≤890ppm

Chlroroethane ≤1000ppm

N, N-Dimethylformamide ≤800ppm

Palladium ≤10ppm

Dichloromethane ≤600ppm

Ivu

≤0.1%

Icyuma kiremereye

≤10ppm

HPLC

3S, 4S tofacitinib ≤0.15%

Suzuma (ku buryo budasanzwe) 98.0-102.0%


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