Amphotericine B 1397-89-3 Antibiyotike
Kwishura:T / T, L / C.
Inkomoko y'ibicuruzwa:Ubushinwa
Icyambu cyo kohereza:Beijing / Shanghai / Hangzhou
Ubushobozi bwo gukora:100kg / ukwezi
Tegeka (MOQ):25kg
Igihe cyo kuyobora:Iminsi y'akazi
Imiterere y'ububiko:hamwe n'umufuka wa ice wo gutwara.Ubike kuri 2-8 ℃ igihe kirekire.
Ibikoresho bipakira:ingoma
Ingano yububiko:25kg / ingoma
Amakuru yumutekano:Ntabwo ari ibintu biteje akaga
Intangiriro
Amphotericine B, irashobora kwitwa Fungizone cyangwa Ambisome, ikaba ari antibiyotike ya polyene antifungal itandukanijwe n’umuco wa Streptomycesnodosus.Yatandukanijwe nibice bibiri hamwe na A na B, ariko Igice ntigikorwa gito kuri antifungal idakoreshwa, abantu rero bakoresha igice B gusa cyiswe Amphotericin B.
Ni imiti igabanya ubukana ikoreshwa mu kwandura indwara zikomeye na leishmaniyasi.Ifite imikoreshereze ibiri itandukanye kumanwa no gutera inshinge.
Amphotericine B niyo ihitamo ryambere kwandura fungal kubera ko ari antifungali.Ifite imikorere ibuza ibihumyo nka cryptococcus, coccidium, candida albicans na blastomycetes, nibindi bizica fugal yibanda cyane, akaba ariwo muti mwiza wo kuvura indwara zanduye.
Ibimenyetso nyamukuru byerekana amavuriro nka: 1. Kuvura ibihumyo nka cryptococcose, blastomycose yo muri Amerika ya Ruguru, ikwirakwiza candidiasis, coccidiose na histoplasmose.2. Kuvura mucormycose iterwa na fungal zimwe na zimwe nka Rhizopus, colporium, endomycetes hamwe nudukoko twa fecal.3. Kuvura sporotrichose iterwa na sporotrichose schenckii.4. Kuvura aspergillose yatewe na Aspergillus fumigatus.5. Imyiteguro yibanze irakwiriye mycose ya pigment.Irakwiriye kandi kwandura uruhu rwuruhu nyuma yo gutwikwa, inzira zubuhumekero Candida na Aspergillus cyangwa kwandura cryptococcus, ndetse no gukora ibisebe bya fungal corneal.
Ingaruka zisanzwe zirimo reaction yumuriro, gukonja, no kubabara umutwe nyuma yimiti itanzwe, hamwe nibibazo byimpyiko.Ibimenyetso bya allergie harimo na anaphylaxis birashobora kubaho.Izindi ngaruka zikomeye zirimo potasiyumu yamaraso make no gutwika umutima.Birasa nkaho bifite umutekano mugihe utwite.Hariho lipide formulaire ifite ibyago bike byingaruka.Ari murwego rwa polyene rwimiti kandi ikora igice mukubangamira ingirabuzimafatizo ya fungus.Igomba kwitonda mugihe habaye ibihe, kugirango umutekano ukoreshwe ugomba gukurikiza inama zitangwa nabaganga.
Ibisobanuro Urwego rwo munwa (Mu nzu isanzwe)
| Ingingo | Ibisobanuro |
| Kugaragara | Ifu yumuhondo kugeza kumacunga yumuhondo, impumuro nziza cyangwa hafi. |
| Kumenyekanisha | IR, HPLC |
| pH | 4.0-6.0 |
| Gutakaza Kuma | ≤5.0% |
| Ivu | ≤3.0% |
| Ibintu bifitanye isano | ≤0.5% |
| 303nm | Umwanda A (Amphotericine A) ≤5.0% Umuntu ku giti cye utazwi ≤1.0% |
| 383nm | Umwanda B (Amphotericine X1) ≤4.0% Umwanda utazwi ku giti cye ≤2.0% |
| Impanuka zose | ≤15.0% |
| Amashanyarazi asigaye | Methanol ≤0.3% Acetone ≤0.5% |
| Suzuma | 50850 amphotericine B ibice / mg kubintu byumye. |
Ibisobanuro Urwego rwo munwa (Mu nzu isanzwe)
| Ingingo | Ibisobanuro |
| Kugaragara | Umuhondo kuri orange powderodorless. |
| Kumenyekanisha | IR, HPLC |
| Ibisigisigi byo gutwikwa | ≤0.5% |
| Ibintu bifitanye isano |
|
| Kuri 303nm | Amphotericine A ≤2.0% |
| Umuntu ku giti cye utazwi ≤1.0% | |
| Kuri 383nm | Amphotericine X1 ≤4.0% |
| Umwanda utazwi ku giti cye ≤2.0% | |
| Umwanda wose | ≤15.0% |
| Amashanyarazi asigaye | Acetone ≤0.5% |
| Methanol ≤0.3% | |
| Imipaka ya mikorobi | Ibara rya mikorobe yo mu kirere ≤1000cfu / g |
| Ibishushanyo & imisemburo ≤100cfu / g | |
| Escherichia coli Kubura muri 1g | |
| Endotoxine ya bagiteri | <1.0EU / mg |
| Suzuma | 50850 amphotericine B ibice / mg, ubarwa ku cyumye |
