Ibicuruzwa

Afoxolaner ni gahundaumuti wica udukokonaacaricideibyo bitangwa mu kanwa cyangwa hejuru.

Afoxolaner irabuzaaside-aminobutyric(GABA) -muyoboro wa chloride (Abakira GABAA) na L-glutamate-umuyoboro wa chloride (GluCls).Imbaraga za Afoxolaner ziragereranywa nafipronil.

Ni udukoko twica udukoko twinshi hamwe nibikorwa byiza byica udukoko turwanya amatiku, ibihuru, inyo, hemiptera na diptera, kandi virusi yayo irarenze cyangwa igereranywa niy’udukoko dukunze gukoreshwa.

Mubuvuzi bwerekana ko Afoxolaner ishobora gutanga ibyumweru 12 kurinda imbwa ingaruka za antibody ectoparasite.Biroroshye cyane kandi neza kubitungwa byombi hamwe ninyamanswa.

Irashobora kwirukana no kwica imbwa.Irashobora gukurikizwa vuba kumashanyarazi akuze kandi ikamara igihe kirekire.Irashobora kandi kubuza ibihuru kwinjira mu magi, bityo bikangiza ubuzima bwimpyisi.Izi nyamaswa zisanzwe ectoparasite zikurura imirire yinyamaswa, kandi zishobora no gukwirakwiza indwara nyinshi, nk'inyo zahiye, indwara ya Lyme, encephalite yo mu mashyamba, n'ibindi. Ntabwo bizagira ingaruka gusa ku mikurire n’ubuzima bw’amatungo gusa, ahubwo bizana ingaruka mbi ku buzima kuri ba nyiri amatungo.Afoxolaner nta gikorwa ifite ku nyamaswa z’inyamabere zakira, bityo rero ni umutekano cyane ku nyamaswa.

Afoxolaner hafi kubora ninyamaswa nto.Imiterere ya molekile yumwimerere igera kuri 90-100% isohoka mumyanda idafite metabolite.Hafi nta gusohora impyiko, umutekano uhebuje, nta kwangiza umwijima nimpyiko zinyamaswa nto.

Ntabwo izwiho kurwanya ibiyobyabwenge hamwe na kirazira yo guhuza ibiyobyabwenge, kandi ntishobora kurwanya udukoko twangiza.Nyuma yo gutangwa mu kanwa, ibiyobyabwenge bikwirakwizwa ku mubiri.Bitangira gukurikizwa nyuma yamasaha 2 nyuma yubuyobozi bwo munwa.Nyuma yamasaha 4, irashobora kwica byibuze 80% yudukoko.Igihe cyo kurinda gishobora kugera ku byumweru 12.Kwandura inshuro nyinshi birashobora kandi kugera ku ngaruka nziza zo kurwanya udukoko.Nubwoko bwa antibody ectoparasite ifite umutekano mwinshi, ikwiriye gukoreshwa.